Polymers in Biochemistry

Proteins are linear polymers built of monomer units called amino acids. The construction of a vast array of macromolecules or polymer structure from a limited number of monomer building blocks is a recurring theme in biochemistry. The function of a protein is directly dependent on its three dimensional structure remarkably, proteins spontaneously fold up into three-dimensional structures that are determined by the sequence of amino acids in the protein polymer. Thus, proteins are the embodiment of the transition from the one-dimensional world of sequences to the three-dimensional world of molecules capable of diverse activities.

Proteins contain a wide range of functional groups. These functional groups include alcohols, thiols, thioethers, carboxylic acids, carboxamides, and a variety of basic groups. When combined in various sequences, this array of functional groups accounts for the broad spectrum of protein function. For instance, the chemical reactivity associated with these groups is essential to the function of enzymes, the proteins which catalyse specific chemical reactions in biological systems

  • Development and evaluation of novel micro particles
  • Preparation of peg/chitosan bio composites
  • Molecularly imprinted hydrogels as potential carriers
  • Spray dried hydroxyapatite-polymer composites
  • Schematic models of biochemical polymers
  • Polymer microfluidic chips for biochemical analyses
  • Reactions and chemistry of polymers

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