Polymer Therapeutics: Concepts and Applications

Polymer therapeutics encompasses polymer–protein conjugates, drug–polymer conjugates, and supramolecular drug-delivery systems. Numerous polymer–protein conjugates with improved stability and pharmacokinetic properties have been developed, for example, by anchoring enzymes or biologically relevant proteins to polyethylene glycol components (PEGylation). Several polymer–protein conjugates have received market approval, for example the PEGylated form of adenosine deaminase. Coupling low-molecular-weight anticancer drugs to high-molecular-weight polymers through a cleavable linker is an effective method for improving the therapeutic index of clinically established agents, and the first candidates have been evaluated in clinical trials, including, N-(2-hydroxypropyl) methacrylamide conjugates of doxorubicin, camptothecin, paclitaxel, and platinum (II) complexes. Another class of polymer therapeutics are drug-delivery systems based on well-defined multivalent and dendritic polymers. These include polyanionic polymers for the inhibition of virus attachment, polycationic complexes with DNA or RNA (polyplexes), and dendritic core–shell architectures for the encapsulation of drugs.

  • Peptide-based polymer therapeutics
  • Polymersomes as polymer therapeutics for drug delivery
  • Polymer therapeutics as nanomedicines
  • Challenges in polymer therapeutics
  • Polymers for drug–protein conjugates

Related Conference of Polymer Therapeutics: Concepts and Applications

April 17-18, 2024

14th International Conference on Chemistry Meeting

Paris, France
June 25-26, 2024

13th World Congress on Chromatography

Toronto, Canada
August 22-23, 2024

16th International Conference on Clinical Chemistry

Berlin, Germany
December 18-19, 2024

4th International Conference on Petrochemistry and Natural Gas

Amsterdam, Netherlands

Polymer Therapeutics: Concepts and Applications Conference Speakers

    Recommended Sessions

    Related Journals

    Are you interested in